Prior predictive — where it appears
Named by 2 essays across 2 fields — each of them below, with the objects they name alongside it.
The chance a trial succeeds
A trial of sixty-four per arm has 80% power at an effect of half a standard deviation. If the effect is only believed to be about half a standard deviation, give or take a quarter, the chance the trial reaches significance is 69.2%; give or take a half, 61.4%. Reaching 80% then takes 113 per arm, or 1,268 — and when the belief is uncertain by three quarters of a standard deviation no number of patients reaches 80%, because the chance can never exceed the 74.8% probability that the effect is positive at all.
When the prior is confident and wrong
A prior worth thirty-five observations, centred in the wrong place, produces a 95% interval that covers nothing at all — and reports a width 5% narrower than an honest one. It takes seventeen thousand observations to repair, not thirty-five, and the worst study to run is the one whose sample size equals the prior's weight, exactly.
Named alongside it
The objects these essays reach for when they reach for this one.
PriorSample sizeAssuranceCoverageCredible intervalEffect sizeFlat priorInterval widthModel misspecificationNormal approximationPilot studyPosterior