Concept

Unmeasured confounding — where it appears

A common cause of two variables that is not in the data, so no adjustment set can block the path through it. Its effect on an estimate has a closed form once its coefficients are named, which is what makes a sensitivity analysis possible without observing it.

Named by 5 essays across 2 fields — each of them below, with the objects they name alongside it.

The first stage an instrument needs is set by the violation nobody can see. The error each estimator converges on when the instrument has a direct effect of 0.05 on the outcome — a path the exclusion restriction asserts is zero and no sample can check. The instrument's error is δ/π exactly, so it is the reciprocal of the very quantity that made the method work: 1.0000 at a first stage of 0.05 and 0.0833 at 0.60. Least squares carries the confounding instead, at 0.3440 at a first stage of 0.30. The two cross at π = 0.1389, and the crossing is exactly δ times 2.7778 — the first stage an instrument needs is proportional to the violation it is assumed not to have, and below that line the method being corrected is the better estimator.

The assumption nothing tests

An instrument buys a causal effect with an assumption no sample can check, and the price is set by the same quantity that made the method work. The first stage it needs is 2.7778 times the violation it is assumed not to have, so a direct effect of 0.05 demands a first stage of 0.1389 and least squares wins below it.

instrument · Exclusion
A covariate that is prior to everything and still ruins it. A covariate measured before the treatment, caused by neither the treatment nor the outcome, and not a common cause of them. Two unmeasured variables sit behind it: one reaches the treatment, the other reaches the outcome, and both reach the covariate. Every rule of thumb for including a baseline variable is satisfied, and the regression that leaves the covariate out estimates the treatment's effect of 0.50 without bias, while the regression that includes it is off by −0.2000 — because the covariate is a common effect of the two unmeasured causes, and conditioning on a common effect makes its causes dependent. The path it opens runs from the treatment back through the first unmeasured cause, through the covariate, and out through the second to the outcome.

A collider before the treatment

A covariate measured before the treatment, on no causal path, and not a common cause of anything, still biases the estimate by exactly −0.2000 against an effect of 0.5 — while the regression that leaves it out is exact. The bias saturates at 0.3536, and the two paths that make it a collider do not appear in that bound.

collider · Conditioning
The same error, caught or invisible, by how it is arranged. The overidentification test's rejection rate against the error the violation actually puts into the estimate, so the two rows are the same estimate being equally wrong. With the whole violation on one instrument the test keeps its size at 5.0% under the null and reaches 86.4% by an error of 0.800. With both instruments violating in the same ratio as their first stages the two Wald ratios are identical, the test has nothing to compare, and it rejects at 5.8% at that same error — its own size. Over 1000 draws of 300 rows at each setting, at a nominal 5.0%. The test is a comparison between instruments and it was never a check on either.

Two instruments that disagree

The overidentification test keeps its size at 5.0% and reaches 86.4% power against a violation carried by one instrument. Against the same error carried by both in proportion to their first stages it rejects on 4.6% of draws — its own size — while the estimate is wrong by 0.3000, which is 94.2% of the confounding the instruments were brought in to remove.

instrument · Exclusion
The covariate the treatment caused, and what it hides. A covariate on the causal path: the treatment causes it and it causes the outcome, so the treatment's total effect of 1.130 runs partly through it. Adjusting for it returns the direct edge alone, 0.500, which is what somebody wanting the total effect should not have asked for. The dashed variable is the second problem: an unmeasured cause of both the covariate and the outcome. It does not touch the treatment, so the unadjusted regression still recovers 1.130 exactly. It does touch the covariate, so once the covariate is conditioned on the treatment and the outcome are linked through it, and the adjusted coefficient lands on 0.050 — neither the total effect nor the direct one.

The variable the treatment caused

Adjusting for a covariate the treatment caused stops estimating the total effect and starts estimating the direct one. When that covariate shares an unmeasured cause with the outcome it estimates neither: the total effect is 1.1300, the direct effect is 0.5000, and the regression returns 0.0500.

collider · Conditioning
A proxy removes less than its reliability, always. The share of the confounding bias removed by adjusting for a proxy, against how well the proxy measures the confounder. The diagonal is the answer a reader would guess — a covariate that is 80% signal removes 80% of the problem. The curve is what the arithmetic gives: the reliability, times one minus the squared correlation between the treatment and the confounder, divided by one minus the product of those two. That squared correlation is 0.4475. A reliability of 0.8 removes 68.85% and one of 0.6 removes 45.32%. The two agree only at the ends, and the gap is widest where most applied covariates sit.

Adjusting for a shadow

A covariate that is 80% signal removes 68.85% of the confounding, not 80% — the share is λ(1 − ρ²)/(1 − λρ²) and it is below the reliability everywhere. The residual bias is 0.1084 against an effect of 0.5, and at 25,600 rows it is 17.6 standard errors wide.

collider · Conditioning

Named alongside it

The objects these essays reach for when they reach for this one.

Adjustment setAsymptotic biasBiasCausal diagramClosed formCovariate adjustmentLatent variableCollider biasExclusion restrictionFirst stageInstrumental-variableObservational equivalence

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