Concept

Conditional distribution — where it appears

The distribution of a quantity given that something else took a particular value. It is what a conditional average is taken over, and it is often the readable object where the unconditional one is not: a regret averaged over draws that are mostly exact zeros spends its precision counting the zeros.

Named by 12 essays across 6 fields — each of them below, with the objects they name alongside it.

The eighth was not a constant. The probability that a per-candidate tuning list changes which candidate the table selects, at each of 5 separations between the candidates, over 800 draws apiece. The earlier field reports this flat at about an eighth across list length, on a table and a world it never varies. Vary how much the omitted coefficients are worth — one multiplier, with the table, the list, the law and the sample size all held — and it runs from 17.6% to 1.5%, a factor of 11.75. The world in which every candidate is true is the world in which the tuning list decides most; the world in which one candidate dominates is the world in which it decides nothing.

The eighth that was not a constant

How often a per-candidate tuning list changes which candidate wins is reported flat at about an eighth across list length. Vary how far apart the candidates are instead and it runs from 17.6% to 1.5%.

turnover · Order-selection
Three mechanisms leave the slope alone; one does not. The bias of the complete-case slope under each of four missingness rules, counted over 4000 studies of 200 rows at 35.0% missing, with the closed form printed beside each count. Missingness that depends on nothing, on the regressor, or on the second covariate leaves the slope exactly where it was — the closed forms are zero to machine precision and the counts are -0.0005, -0.0005 and -0.0011 against standard errors of about 0.0018. Missingness that depends on the outcome moves it by -0.1635, which is 27.3% of the slope being estimated. The same share of rows is lost in every case.

Three mechanisms and one dataset

Four rules for which outcomes go missing, each calibrated to lose the same 35% of the rows and each leaning on what it reads with the same coefficient. Three leave the fitted slope exactly where it was, and the one that reads the outcome moves it by 0.163531.

missing · Missingness
Two factors, opposite directions. The two factors the cost of a per-candidate tuning parameter is a product of, as the candidates are pulled apart, over 800 draws at each of 5 separations. How often the candidates disagree about the tuning parameter rises from 31.8% to 88.8%; the share of those disagreements that change which candidate the table selects falls from 51.6% to 1.7%. So the setting where the candidates quarrel most about the tuning parameter is the setting where the quarrel matters least, and a sweep that reads the rate and stops has read the factor pointing the wrong way.

Two factors pointing opposite ways

As the candidates on a table are pulled apart, they quarrel about the tuning parameter three times as often and the quarrel decides the winner thirty times less often. A sweep that reads the first factor has read the one pointing the wrong way.

turnover · Order-selection
Unrepresentative in every respect but the one that matters. Three properties of the complete cases as the chance of being observed leans harder on the regressor, in closed form, at 35.0% of outcomes missing throughout. The mean of the regressor among the rows kept climbs from 0.0000 to 0.5528 against a population mean of zero, and the mean of the outcome from 0.0000 to 0.3980 above its own. The bias in the fitted slope is exactly zero at every one of the ten settings, because selection acting on the regressor alone leaves the conditional law of the outcome given the regressor untouched and least squares conditions on exactly that. The sample is wrong about almost everything and right about the one quantity being estimated.

Dropping the incomplete rows

Push the missingness until the rows that survive have a covariate mean of 0.543905 against a population zero and a variance of 0.5041 against one, and the fitted slope is still exactly right. Where the rule reads the outcome instead, the same sweep takes coverage to 2.42% at eight hundred rows.

missing · Missingness
Flat along a row, apart between them. The probability that a per-candidate tuning list changes the winner, at three list lengths on three candidate tables, over 800 draws in each of the nine cells. Along a row — the reading the earlier field takes — it moves by a factor of at most 1.21, so that field's invariant survives on every table. Down a column it moves by up to 1.98. The list length is the dial that does not move this number and the table is one that does, and the earlier field varied only the first.

A table and a list

A nested ladder of candidates differing by one coefficient was predicted to turn over more often at every list length. It turns over less at every one, and its list changes the winner half as often.

turnover · Order-selection
Exact coverage, at every block size. Coverage of the interval each rule reports, at a nominal 95%, over 2,500 runs each with a standard error of 0.44 points. The blinded rule stops on the within-block contrasts and reports an interval built from the block means, and those two are independent whatever the rule does — so the interval is an ordinary t interval on b − 1 degrees of freedom and its coverage is exact. It is exact at every block size drawn. The interval a practitioner writes at the purely sequential rule's stopping time covers 91.72%, and Stein's two-stage rule is exact for the same reason as the blinded rule and spends 2.10 times the observations to be so. The bars are truncated at 86% so the differences can be seen.

The rule that cannot see the mean

A sequential rule stops when its own estimate of the spread is small, which is more often on the samples whose spread came out low — so the interval afterwards is short. There is a way to keep updating the estimate and stop being able to see the mean at all.

blind · Stopping
Forty O'Brien–Fleming trials at a true effect of 0.16, with the boundary written as an effect. The dashed line is the smallest effect a trial can report and still stop at each look: 0.510 at 80 observations, 0.255 at 160 observations, 0.170 at 240 observations, 0.128 at 320 observations, 0.102 at 400 observations. The true effect is 0.16, so at 3 of the five looks a trial cannot stop without reporting more than it. 29 of these forty trials stop before the last look, each marked where it stopped.

The effect a stopped trial reports

An O'Brien–Fleming trial at 88.45% power holds its error rate exactly and reports an effect 9.6% too large on average. The 11.39% of trials that stop at the second look report 1.83 times the truth, the ones that cross at the last look report 0.80 times it, and pooling every trial by its size gives the truth back to the last digit.

sequential · Stopping
What a fixed-width interval covers, by the number of blocks the trial ran before it stopped. Two thousand runs of each rule, the modelled weighting, a promise of 0.34. Reading its report: 4–8 blocks, 22.3% of runs, 78.2%; 9–12 blocks, 16.6% of runs, 90.4%; 13–16 blocks, 18.4% of runs, 96.2%; 17–20 blocks, 17.4% of runs, 96.0%; 21–28 blocks, 17.9% of runs, 96.4%; 29–36 blocks, 7.4% of runs, 99.3% — 91.45% overall. Reading the arms: 4–8 blocks, 0.0%, none; 9–12 blocks, 0.9%, 94.4%; 13–16 blocks, 30.4%, 95.6%; 17–20 blocks, 50.0%, 93.9%; 21–28 blocks, 18.0%, 94.4%; 29–36 blocks, 0.7%, 92.3% — 94.50% overall.

The trials that stopped early

A fixed-width trial that stops when its own interval is short enough covers 91.45% — an average of 78.2% among the 22.3% of runs that stop within eight blocks and 96% to 99% among those that run longer. Widening every interval by 17.1% brings the average to 95% and leaves the early stops at 85.6%, while 92.8% of runs now report an interval wider than the width they promised. Even doubling every interval leaves the early stops short.

stop · Width
The same dial, on a list that steps by one. The probability that a per-candidate tuning list changes which candidate the table selects, at each of 5 separations, for both tuning parameters at a matched list length of 8. The sieve order runs from 13.1% to 2.6%, a factor of 5.00; the whitening window, from 16.4% to 1.5%, a factor of 11.75. What is held is the number of options, the table, the law, the sample size and the seeds; what cannot be held is the size of a step, since an integer step and a geometric step are different amounts of change. The dial moves both, and it moves them by 2.35 times as much on one as on the other.

A step that is not a ratio

Run the separation sweep on a tuning list of integers rather than a geometric ladder and the two factors still point opposite ways. The invariant does not survive: along a row of integers the probability moves by 2.163 where along the geometric ladder it moves by 1.208.

turnover · Order-selection
Ordered stagewise: the outcomes at least as extreme as stopping at 160 observations with z = 3.3. Each column is one look of an O'Brien–Fleming trial; above the boundary a trial stops there. Highlighted are the outcomes that count as at least as extreme as the observed one when outcomes are ordered stagewise: at 80, z ≥ 4.56 (probability 2.54 × 10⁻⁶ with no effect); at 160, z ≥ 3.30 (probability 4.82 × 10⁻⁴ with no effect); at 240, none; at 320, none; at 400, none. The two-sided p-value is 9.69 × 10⁻⁴.

The outcomes a trial could have stopped with

A trial that stops at its second look with z = 3.3 has a two-sided p-value of 0.000969, 0.000987, 0.00187 or 0.0421, depending on how the outcomes it could have stopped with are ordered. One of the four orderings does not change when the looks the trial never reached are replanned, and the same one gives a trial that ran to the end with z = 6 a p-value of 0.0256.

sequential · Stopping
The line is the sample, and the sample is the finding. 900 draws of two independent standard normal causes, with the 453 of them past a threshold of 0.00 marked and the 447 that fall short left pale. In the population the two are independent by construction. Inside the selected sample the correlation is -0.4669 in closed form and -0.5050 counted on these 453 rows, and the least-squares line through them has a slope of -0.545. The mechanism is visible in the picture rather than argued: the threshold removes one corner of the cloud, and a cloud with a corner missing is a cloud whose two coordinates carry information about each other.

The sample is a condition

Two independent standard normals, selected on their sum exceeding its median, read a correlation of exactly −1/(π − 1) = −0.4669 inside the sample. Nothing is measured badly and nothing is missing — and both halves of that split read it, in the same direction, while the population containing both reads zero.

collider · Conditioning
The damage does not stay in the term that was left out. Where each coefficient lands when the model that fills the missing outcomes and the model that analyses them disagree, over 1500 studies of 200 rows at 35.0% missing and 20 imputations. An imputer that omits a covariate the analysis fits attenuates that covariate's coefficient by exactly the missing fraction — -0.1405 counted against a closed -0.1400 — and pushes the coefficient it did impute on the other way by exactly the product of the omitted coefficient, the covariates' correlation and the missing fraction: 0.0402 counted against 0.0420. Both closed forms come out of the same two-by-two solve. Matching models leave both alone, and so does an imputer that knows more than the analysis.

An imputation model the analysis does not contain

A model that fills the gaps without a covariate the analysis fits attenuates that covariate's coefficient by exactly the missing share, 0.4 to 0.26, and moves the one it did carry by exactly γρf, 0.6 to 0.642. The reverse case is supposed to inflate the interval, and at four strengths of the extra knowledge it does not.

missing · Missingness

Named alongside it

The objects these essays reach for when they reach for this one.

Monte CarloClosed formBandwidth selectionConfidence intervalDependenceInformation criterionModel selectionNested modelsOrder-selectionOverfittingRegretSelection bias

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