Normal Distribution
nothing is called 95% until it has been counted
Concept

Standard deviation — where it appears

The square root of the variance, in the same units as the quantity itself. It is what an imbalance or a difference is usually reported in multiples of, which is what makes those numbers comparable between experiments.

Named by 16 essays across 10 fields — each of them below, with the objects they name alongside it.

Every split of 100 units, σ = 1 against 3. Each point is one integer split, with its variance computed exactly rather than simulated. The minimum is at 25:75, which is the ratio of the spreads 25:75, and equal allocation costs 25% more variance — the same as throwing away 20 of the 100 units. The shaded band is every split within 5% of the best, and it runs from 17% to 35%: sharp to state, flat to sit on.

Not half and half

The same units, the same measurements, the same analysis — and a different variance, decided before anything is measured. When the two arms have different spreads the best split is σ₁ : σ₂, equal allocation costs 2(σ₁²+σ₂²)/(σ₁+σ₂)², and at three to one that is a quarter of the experiment.

allocation · Allocation What x-bar plus or minus 2 sample standard deviations holds, at n = 10. The content of the band is a random variable. Across 20,000 normal samples of 10 it averages 91.1%, its fifth percentile is 74.7%, and it falls short of 95% on 59.9% of samples. The band that is drawn to show where 95% of the data lies.

Two standard deviations of what

The 95.45% inside two standard deviations is a fact about a curve whose centre and width are given. Drawn from ten observations, the same band holds 91.1% on average and less than 95% on 59.9% of samples — and the average is the reading that hides it.

estimated · Bands The power trials actually have when sized for 80% from a pilot of 10. Four thousand pilots of 10 observations, each sizing a trial for 80% power at half a standard deviation from its own standard deviation. 55.9% of the trials have less than 80% power and 11.1% less than 50%; the median trial has 76.8%.

The spread a pilot supplies

A trial sized for 80% power from a pilot's standard deviation is sized from an estimate that is too small more often than not. With a pilot of ten, 55.9% of the trials it sizes have less than 80% power and 11.1% less than 50%, although the planned sample is right on average. Sizing from the pilot's 80% upper confidence limit instead leaves 19.8% short, at 1.65 times the sample; from its 90% limit, 10.0% short at 2.12 times.

planned · Power Every way of splitting 16 units into two halves. All 12,870 assignments, enumerated. The spread of the standardised imbalance is exactly 2/√n = 0.500, whatever the covariate's own distribution, and 33.3% of assignments differ by more than 0.5 standard deviations. Randomisation does not deliver balance; it delivers a known distribution of imbalance.

Randomisation is not balance

A third of all ways to split sixteen units leave the two halves more than half a standard deviation apart on a covariate. What randomisation delivers is not balance but a known reference distribution — and it makes a test exact with no assumption about the data's shape at all.

design · Randomisation Where the normal approximation converges, and where it does not. Relative error against the exact binomial. At n = 1280 the error at the median is 0.96% and three sigma out it is 25.7% — a factor of 27. The tail is where the approximation is used.

The tail converges last

The central limit theorem is usually shown as a shape arriving. What the demonstration leaves out is the rate — and the rate is wildly different in the middle and in the tail, which is where every approximation in the subject is actually read.

normal · Rate Twenty walks up the same hill, σ = 2. Each walk fits a plane to the same four-corner factorial, takes its gradient as a direction, and steps along it until a run comes in below the one before. The true optimum is the cross. 80% of the walks stop before the best point on their own path — not because the direction was wrong, but because one noisy run is enough to stop them, and the direction error costs only 3.9% of the available gain.

Walking up the gradient

The fitted gradient is wrong by an angle with a closed form, σ/(|β|√N), and what that angle costs is its squared cosine — twelve per cent at twenty degrees. What costs a third of the gain is not the direction at all. It is deciding where to stop.

surface · Optimum Power at an effect of 0.5 standard deviations. The curve is the non-central t on 2n − 2 degrees of freedom with δ = d√(n/2); the dots are 4,000 experiments run at each size. Reaching 80% power needs 64 per arm.

What a p-value does not say

The same p of 0.04 corresponds to a large effect in ten observations and a negligible one in two thousand. A p-value alone cannot be interpreted, and the number that makes it interpretable is almost never printed beside it.

testing · Power Three bands called 95%, at n = 20. Half-widths in sample standard deviations: 0.468 for the mean, 2.14 for one future observation, 2.75 to hold 95% of the population. The first two differ by exactly the square root of n + 1, which is 4.58 here.

A tenth as wide, and both of them right

The interval for a mean and the interval for one future observation are both labelled 95%, and at a hundred observations one is 10.05 times the other — exactly the square root of n + 1. Read the narrow one as the wide one and it covers a new value 15.7% of the time.

estimated · Bands Least squares estimates persistence low, by an amount with a formula. 3000 series of 50 observations at each persistence. The lower curve is the counted bias of the least-squares estimate of φ, and the open marks on it are −(1 + 3φ)/n, computed rather than fitted. The upper curve is the bias left after adding that quantity back, evaluated at the estimate rather than at the truth nobody has: -0.0020 at φ = 0.3, -0.0023 at φ = 0.5, -0.0039 at φ = 0.7, -0.0059 at φ = 0.8, -0.0108 at φ = 0.9, -0.0165 at φ = 0.95. The formula is a leading-order expression and it understates the bias where the persistence is nearest one — -0.0882 counted against -0.0770 predicted at φ = 0.95, which is the corner of the parameter space every one of these approximations is worst in.

Correcting the persistence

Least squares estimates how much a series remembers of itself as smaller than it is, at every value it can take, by an amount with a closed form. Subtracting that amount back is one line of arithmetic, and what the line costs is variance.

evaluation · Bias Two measurements of the same thing, correlated 0.60. Pick the worst 15% on the first measurement and their average rises by 0.78 on the second. Pick the best and theirs falls by 0.48. No treatment was given to anybody.

Regression to the mean

Select the worst performers, measure them again, and they improve. Select the best and they decline. No intervention is required for either, the size of the apparent effect is predictable from the correlation alone, and it is the reason so many things appear to work.

paradox · Rtm 12,000 studies of a real effect of 0.3, n = 16. Power is 21%. The studies that reached significance report a mean effect of 0.621 — 2.07 times the truth. Every one of them is honest; the selection did the inflating.

The winner's curse

Filter honest studies down to the ones that reached significance and the effects they report are systematically too large. At low power the inflation is a factor of two, nobody has done anything wrong, and the selection did all of it.

testing · Curse Twenty 95% intervals for a proportion that really is 0.35. 2 of the twenty miss the true value. The 95% is a property of the procedure across repetitions — no single interval has a 95% chance of anything, because it either contains 0.35 or it does not.

Twenty intervals and one expected miss

The 95% belongs to the procedure, not to the interval in front of you. Twenty intervals from twenty samples make that visible in a way no definition does, and the one that misses is not a mistake.

intervals · Repetition What a pilot buys, σ = 1 against 3. Each point is 6,000 two-stage experiments of 100 units: a pilot of m per arm, then the rest split by the pilot's own estimate of the two spreads. Above the line the pilot has made the experiment worse than not bothering. The best pilot here is 8 per arm at 0.809, against 0.800 for a designer who knew the spreads — so the rule recovers 96% of what knowing them is worth. A larger pilot estimates the ratio better and has less left to apply it to, which is why the curve turns.

Allocating on a guess

Every allocation rule in this field is a function of quantities the experiment is being run to find out. Fed a pilot's estimate of them, the rule that minimises the variance makes the experiment worse than not bothering — until the arms differ by about a factor of two, which is further than anyone would guess.

allocation · Allocation Power at an effect of 0.5 standard deviations. The curve is the non-central t on 2n − 2 degrees of freedom with δ = d√(n/2); the dots are 4,000 experiments run at each size. Reaching 80% power needs 64 per arm.

How many subjects

Sixty-four per arm for 80% power at half a standard deviation — a power figure that could only be simulated, with nothing to disagree with, until the non-central t was written. Two routes now, agreeing to within the simulation's own error.

design · Power The normal density at sigma = 1.00. The bands hold 68.27%, 95.45%, 99.73% of the mass. Those figures are integrals of the curve drawn, not the memorised 68-95-99.7.

The shape, and where its mass is

68, 95, 99.7 is recited more often than any other set of numbers in the subject. They are integrals of a specific curve, they are worth computing rather than remembering, and the third one is the one people misuse.

normal · Bands Student's t on 5 degrees of freedom, against the normal. The two-sided 95% critical value is 2.571 for t(5) and 1.960 for the normal — 31% wider. Using the normal at this sample size makes every interval too short by that much.

The correction for not knowing the spread

The t distribution exists because the standard deviation is estimated rather than known. At eight observations, using the normal instead makes every interval 12% too short — and the coverage that follows can be measured rather than argued about.

intervals · Student

Named alongside it

The objects these essays reach for when they reach for this one.

Sample sizeEstimated varianceStatistical powerAllocationCoveragep-valueExperimental designPlug in estimateAllocation ratioBlockingConfidence intervalDegrees of freedom

All concepts