Concept

Sequential — where it appears

Deciding whether to continue from the data already collected, so the sample size is a random variable. Everything computed at the end has a distribution that depends on the rule, which is why an unreported stopping rule leaves those numbers uninterpretable.

Named by 2 essays across one field — each of them below, with the objects they name alongside it.

The construction survives a difference of two weighted means. Coverage of δ̂ ± t√(S_D²/H) on b − 1 degrees of freedom, over 900 runs at a requirement of 0.3, where δ̂ is the block differences weighted by h_b = (1/m_A + 1/m_B)⁻¹ and H is their total. The theorem the one-mean field rests on goes through with h_b in place of the block size, and the reason is that the weights a weighted least squares decomposition needs are the inverse variances — which is exactly what h_b is. The stopping rule reads only within-arm within-block contrasts, so it is a function of nothing the interval reports, whatever it does with the block sizes. Each bar is within 2.9% of the level it claims.

A width promised for a difference

The exact fixed-width interval was built for one mean. Two arms make the target 42.7 units of effective size and each unit costs four observations, so the same promise about a difference costs 169.4 rather than 42.7 — and the theorem survives untouched with the harmonic size in place of the block size.

contrast · Width

Free until the sums stop seeing what the differences see. Coverage with and without the block sums pooled into the interval's variance estimate. With one effect and one level they are free. With an effect that varies between blocks they are still free, because a block's sum picks that variation up exactly as its difference does. With a level that varies they make the interval 37% wider and conservative. And where the effect falls as the level rises — a ceiling, and not an exotic thing to suppose — the sums carry none of the between-block variation while the differences carry all of it, the pooled estimate is short, and the interval that uses it covers 88.75% on a width 20% narrower than the honest one.

What a two-arm rule may not pool

A spread computed "within the block" without the arm label carries a share of the effect, so the trial runs 173 observations at a null and 282 at an effect of 1.5. The stopping rule is reading the thing it exists to measure, and the phrase that produced it is one word long.

contrast · Allocation

Named alongside it

The objects these essays reach for when they reach for this one.

Allocation Blinding Confidence interval Contrast Coverage Degrees of freedom Fixed-width interval Stopping rule Two-sample Block Effective sample size Harmonic mean

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